Data Splitting for Seurat object
Usage
ds(
sce,
params1 = NULL,
params2 = NULL,
seed = NA,
test.use = "t",
signal_measurement = "tstat",
test.from.raw = TRUE
)
Arguments
- sce
A SingleCellExperiment object
- params1
list of parameters to be passed to
perform_clustering
for the first half of the data splitting- params2
list of parameters to be passed to
perform_clustering
for the second half of the data splitting.- seed
random seed for reproducibility
- test.use
The hypothesis testing for DE test. Possible choices:
t
,wilcox
,poisson
, andnegbinom
- signal_measurement
the signal measurement. Possible choices: the test statistic
tstat
, or the signed p-valuepval
- test.from.raw
whether to perform the testing on the original data without normalization or on the normalized data